COMPOUND GlucoraphaninENZYME MyrosinaseCLASS IsothiocyanateSOURCE Brassica oleraceaFORM Whole-plant powder

Meticulously made.Molecules, crafted in the healthiest plant cells we could grow.

Gracious manufactures pharmaceutical-grade sulforaphane bioactivity at a consumer supplement price, by growing the plant and its activating enzyme under controlled conditions instead of reconstructing the molecule in a reactor.

500 u/g
Myrosinase activity, against an industry standard near 120 u/g
$6-$12
Cost per mg of sulforaphane, in shelf-stable precursor form.
6 mo
Room-temperature shelf life, against roughly one month
$60-$90
Retail price for daily use or maximum strength versions.
01

Mechanism of action

PRECURSORGlucoraphaninENZYMEMyrosinase+HYDROLYSISACTIVE MOLECULESulforaphaneFormed on contact, not beforeTARGETKEAP1 complexNrf2 releasedNUCLEUS · ARENrf2 transcriptionMore than 100 cytoprotective,antioxidant and phase IIdetoxifying genesIn many tumour cells KEAP1 is already mutated and Nrf2 is constitutively active, so thesame compound does not amplify the pathway there. That differential is why the research exists.
Solid line primary pathwayDashed line differential response in tumour tissueSource peer-reviewed literature, see Evidence

The molecule does not pre-exist

Broccoli contains a dormant precursor and, stored separately, the enzyme that activates it. Sulforaphane exists only when the two meet.

Most processing destroys the enzyme

Conventional manufacture separates or inactivates myrosinase, so the capsule delivers a precursor rather than an active compound. That is the absorption gap.

We manufacture both, together

Whole plant material keeps precursor, enzyme and the surrounding molecular complex intact and in ratio, which is the form the body is equipped to absorb.

02

Specification and quality control

Certificate of analysis · representative batchLot GR-SFN-0114 · Facility 001
AttributeGraciousIndustry referenceResult
Myrosinase activity500 u/g~120 u/gPASS
Cost per mg of sulforaphane, in shelf-stable precursor form$6-$12~$132PASS
Stability, 25 °C6 months~1 monthPASS
Pesticide residueNDVariablePASS
Monthly cost to patient$60-$90~$1,228PASS

Platform developed and lab-validated with Standard Process, Eurofins and Creative Enzymes. Myrosinase produced at UNC Charlotte. Industry reference for patient cost reflects institutional-grade sulforaphane products. ND = not detected. Representative values shown; the current lot certificate is published with every batch.

Grown under containment

Crops are cultivated indoors under precision-controlled conditions. No pesticides or herbicides are applied, so no aggressive wash step is needed, and the delicate actives survive to the finished powder.

Drug-free by definition

Every Gracious product is whole plant material. No synthesis, no isolates reconstructed in a reactor, no excipients, nothing requiring a prescription.

Published, not asserted

Each batch is tested by an independent laboratory and the certificate is published. If the assay is not shown, the product should not be bought.

03

Product pipeline

BMI
SFN-01 · 25 g

Daily metabolic and detoxification support for weight maintenance after GLP-1 discontinuation.

Commercial · dietary supplement
~20M U.S. adults
Chemo
SFN-01 · 25 g

Daily whole-plant sulforaphane taken alongside oncology care, at a purity grade appropriate for immunocompromised patients.

Commercial · dietary supplement
~2M diagnoses / yr
Recovery
SFN-01 · 28 g

Oxidative-stress support between training sessions. No banned substances, no proprietary blend.

Commercial · dietary supplement
Athletes, general
Next bioactives
Platform expansion

Roughly 50,000 plant bioactives are documented in the literature and almost none are commercially available, because legacy platforms could not grow them economically.

Development · cultivation
Multiple
Plant-derived APIs
Long-range

Active pharmaceutical ingredients grown rather than synthesized, as population safety data accumulates on the consumer side first.

Exploratory
To be determined

All three commercial products are regulated as dietary supplements under DSHEA, not as drugs. Stage indicators describe commercial and development readiness, not clinical trial phase. Gracious does not sponsor clinical trials; independent trial references appear under Evidence.

04

Process

A whole new way to grow molecules naturally, at scale — inside buildings the supply chain left behind.

Pharmaceutical-grade molecules are usually synthesized in reactors or extracted from field crops at the mercy of weather and soil. We do neither. Each farmacy is a living production line: a rescued industrial building upfitted into stacked, palletized growing floors where the plant makes the molecule and the building makes the conditions — every lot assayed on site before it reaches the counter downstairs.

The building itself runs as one metabolism. Food waste, rain water and solar light power the aquaculture that grows our greens; rain water grows the mushrooms and the medicine; and our waste streams leave as organic fertilizer and a brownfield remediator. Because every building is unique, every farmacy grows a different mix of the products we know how to grow — the building decides.

Five steps, repeated fifty times, never identical
01Site selectionDead industrial buildings inside the walking radius — bones, roof area and freight access decide.
02GuttingDown to structure and envelope; brick, timber, steel and glass block are salvaged and reused on site.
03UpfittingPalletized grow bays, the aquaculture loop, rain cisterns, the assay lab and the market counter go in.
04ProductionThe closed loop starts turning, pallet by pallet — every lot assayed on site before it is sold.
05ToursPublic tours, school visits and markets open the growing floors to the neighbourhood. Tours are the audit.
5
Steps from vacant building to open farmacy
1
Closed loop — food waste, rain water and solar in; food and medicine out
0
Synthetic reactors — the plant makes the molecule, naturally
50
Buildings planned, each growing its own mix of products
05

Evidence

The following are independent publications on sulforaphane and the Nrf2 pathway. They are provided for professional reference. They are not claims about Gracious products, and none of this work was sponsored by Gracious.

01Calcabrini C, et al. Sulforaphane potentiates anticancer effects of doxorubicin and cisplatin and mitigates their toxic effects. Front Pharmacol. 2020;11:567.
02Bose C, et al. Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. Cancer Res. 2018;78(13):3582–3592.
03Guerrero-Beltrán CE, et al. Sulforaphane protects against cisplatin-induced nephrotoxicity. Toxicol Lett. 2010;192(3):278–285.
04Wang X, et al. Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis. Sci Rep. 2016;6:36796.
05Hegde M, et al. Harnessing sulforaphane potential as a chemosensitizing agent: a comprehensive review. Cancers. 2024;16(2):244.
06ElKhalifa D, et al. Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials. Front Oncol. 2023;13:1251895.
07Shapiro TA, et al. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. Cancer Epidemiol Biomarkers Prev. 2006.
08ClinicalTrials.gov NCT03934905. Protective effects of sulforaphane on doxorubicin-associated cardiac dysfunction. Texas Tech University HSC. Independent trial; not conducted or funded by Gracious.

Important product information

Gracious products are dietary supplements, not drugs. These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure or prevent any disease.

  • If you are receiving cancer treatment, talk to your oncologist before adding any supplement to your regimen. Sulforaphane upregulates phase II detoxifying enzymes and may interact with some therapies, including immunotherapy.
  • If you are pregnant, nursing, or managing a chronic condition, consult a qualified healthcare professional before use.
  • Discontinue use and seek advice if you experience an adverse reaction. Adverse events can be reported to hello@getgracious.com.
  • Keep out of reach of small children except as directed by a healthcare professional.

Statements describing the effect of a nutrient on the structure or function of the body reflect the company's thesis and the cited independent literature. They are not a representation that any Gracious product has been shown to produce a clinical outcome.

We grow to order, so supply is allocated.

Clinicians, retail partners and building owners can request access to current lot availability, the full specification package and facility partnership terms.

Reserve